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He et al., 2008

Increase in liver M2 cells in aged animals [43], involvement of lysosomes in Gd (III) accumulation in macrophages and in their proliferation [100], leukocytic infiltration, at the renal level with tubules atrophy [50], enhancement of neutrophil elastase activity [35], and alteration in leukocyte count [37,68] were also reported

Those listed in the figure as possibilities for the period 20152065 are those currently known by the authors as being pursued, but do not represent all possibilities

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