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instead, it upregulates beta3-AR RNA expression in adipocytes, restoring receptor density in obese models to levels observed in lean animals

After 6 weeks, the patients receiving tanezumab experienced a significant reduction in LBP compared to that of the other two groups

Numerous clinical studies have shown that regular physical exercise can significantly improve insulin sensitivity by promoting the translocation of glucose transporter proteins to the cell membrane in skeletal muscle cells, thus enhancing glucose uptake and utilization in peripheral tissues (Liu et al., 2023)

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