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A differential search included 16 Da for methionine oxidation

DeFrank, S.P

Here are some general guidelines: Mild deficiency: The typical treatment is a 250-500 mcg liquid B12 dose prescribed to patients with the mildest B12 deficiency
Its a fundamental part of the scientific process

Am J Physiol Endocrinol Metab 296, 256-261 (2009)