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PMID: 9918219

Individuals who inherit several copies (duplications) of the wild-type allele are labeled as rapid or ultra-rapid metabolizers and degrade specific drugs more quickly targeted by a particular enzyme and less effective in treating the illness

77 found that ferroptosis was functionally relevant in vivo in acute tubular necrosis and ischemia/reperfusion (I/R) injury and showed that a ferroptosis inhibitor, a new third-generation ferrostatin (termed 1686), protected against this injury

10.1073/pnas.87.12.4879 93 FussJ

The version of PFK-1 encoded by the PFKL gene undergoes phosphorylation during periods of glucose deprivation