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Combined treatment of DSF and Cu, but not either agent alone, significantly increased CCL5 and CXCL10 mRNA levels at low concentrations (Fig

Gilbert JA, Blaser MJ, Caporaso JG, Jansson JK, Lynch SV, Knight R

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However, various internal and external factors can disrupt this balanced distribution, causing melanin to accumulate in specific areas and creating the characteristic dark spots associated with hyperpigmentation

Ramos, S
