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Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese

Polysaccharides 5, 241287

The maintenance of intracellular copper homeostasis is mainly dependent on the above copper chaperone proteins and copper transporter proteins, the imbalance of copper homeostasis will lead to cellular metabolic disorganization and even death [45]

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In diagnostics and monitoring, FRGs such as System Xc and MCU correlate with prognosis, molecular subtypes, and the distinction between precancerous lesions and early tumors [146, 173, 207]