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There are no adverse side effects with the doses used for skin brightening

Tell your doctor if you take any other medications, including prescribed, over-the-counter, or herbal types, particularly: You must use contraception while taking the Wegovy pill because it is not known whether semaglutide is safe during pregnancy

Neurochem Res 49(5):12911305

For individuals receiving B12 injections for severe deficiency, there have been isolated reports of hypokalaemia (low potassium) during initial treatment, as rapid cell production consumes potassium

You could also consider a SAMe supplement, but bear in mind it is a medicine in some countries, and there is some evidence that it can imbalance the system and downregulate endogenous SAMe synthesis
