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Whilst the NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, there is generally no benefit to consuming such excessive amounts unless treating confirmed deficiency under medical supervision

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23.Kaminetsky J, Werner M, Fontenot G, Wiehle RD

Some comes from metabolic adjustments as the body shifts energy sources

Overdosage and Emergency Protocol Taking an amount of Vitneurin Vitamin B Complex Injection may result in effects and should be promptly addressed