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Conclusion Lactate metabolism and lactylation metabolic processes mediated by LDHA, GLO1, GLO2 and D-LCR are important mechanisms by which lactate affects the growth of P

For understanding the binding of the four selected compounds to GPX4 protein showing the mechanism of the interaction, molecular docking analysis and molecular dynamic (MD) simulation were used

These compounds directly or indirectly exhibit antioxidant properties which can sustain the intracellular redox status and these activities protect the healthy cells from reactive oxygen species induced oxidative damage

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