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For example, mitochondrial ROS (mtROS) directly sulfenylated uncoupling protein 1 (UCP1) in brown adipose tissue, leading to promoted thermogenesis, energy expenditure and consequently loss of weight [86]

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GDAP1 -deficient cells also show increased levels of eIF2 and ER chaperones like BiP and GRP94, indicating that a reduction in GDAP1 triggers ER stress as well [13]