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However, other groups have shown that efficient mTORC1 suppression is necessary to avoid MZB loss 39

doi: 10.1152/physrev.00041.2018 7
Proc Natl Acad Sci U S A 66:500506 Folbergrov J, Passonneau JV, Lowry OH, Schulz DW (1969) Glycogen, ammonia and related metabolities in the brain during seizures evoked by methionine sulphoximine

ALS: bulk of the iceberg Human neuroimaging and post-mortem studies show that impaired mitochondrial biology occurs early in the pathogenesis of ALS [54]
It also helps in enhancing immunity
