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A similar RDP study with 53 men with erectile dysfunction showed a decrease of total and LDL cholesterol by 20 and 21%, respectively, in the diabetes mellitus type 2 subgroup taking 120 mg Pycnogenol daily for three months ( , total cholesterol decreased significantly by 9% and LDL-cholesterol decreased significantly by 14%

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This trend has been consistently observed in rodent models, both following in vivo (5, 9, 64, 67, 116) and in vitro (84, 116) treatments, with a range GA regimens and analysis timepoints