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Smith, 1948) and the structure, described by Hodgkin et al

doi: 10.1038/s41577-019-0210-z 77 ChristofidesAStraussLYeoACaoCCharestABoussiotisVA

Briefly, TRPs are Ca 2+ -permeable channels known for their role in temperature sensation, but interestingly, have also been shown to play a role in the release of pro-inflammatory cytokines from microglia in mice exposed to immunogenic agents [i.e., lipopolysaccharide (LPS)] (Zhang Y

Challenges of large-scale synthesis, reproducibility issues, long-term biodegradability, immune interactions, and regulatory approval need to be addressed systemically