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Roa et al., 2009)
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
Post-mortem studies and patient-derived models consistently show features of mitochondrial dysfunction, such as swelling, fragmentation, and vacuolization, particularly in motor neurons [197,198,199,200]
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MDHAR4 mutants also have lower ascorbate to DHA ratios, but have similar total ascorbate levels to the wild type (Eastmond, 2007)
