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For example, the reaction of carbonyl compounds with a Grignard or organolithium reagent is 1,2-addition: Both the Grignard and especially organolithiums are very strong bases, and stronger bases tend to give 1,2 carbonyl addition reactions while weaker bases give 1,4 conjugate addition

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Furthermore, the energy metabolism of AML cells demonstrates high heterogeneity, complexity, and diversity, suggesting that the regulatory role of autophagy within it is also complex and variable

In 1991, we presented evidence that bacteria require the periplasmic protein DsbA for efficient formation of these bonds