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Author contributions All authors above made substantial contributions to the conception or design of the work or the acquisition, analysis or interpretation of data for the work and drafting the work or revising it critically for important intellectual content and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved

Even though the structure and function of the cannabinoid structure have been extensively studied, there are still many unanswered questions, particularly in regards to the systems role in immunity (i.e., immune cannabinoid system)

In a feeding study involving 45 healthy subjects, the mean conversion rate of glucosinolates (of which 85% was glucoraphanin) to dithiocarbamates over a 24-hour period was estimated to be around 12% with wide variations among participants (range, 1.1 to 40.7%) (6)

It might not be safe for people with: Allergies to vitamin B12 Lebers disease, which affects eyesight Kidney issues Low potassium levels Not having enough other important nutrients like folic acid and iron

Many longevity-focused patients repeat cycles 2-4 times per year as part of a comprehensive healthspan optimization program