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The total length of the gene is about 18.5 kilobases (kb), much of which (about 12 kb) consists of intron 2

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Spheres containing a minimum of six cells were scored

Neuroinflammation plays critical roles in MS pathogenesis consisting in dysregulation of inflammatory cell events in the brain, resulting in BBB disruption, damage of myelin and oligodendrocytes, neuro-axonal damage and inflammation (Haase and Linker, 2021)

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