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16 Gpx1 may have a limited antioxidant role under normal physiological condition because Gpx1-deficient mice are healthy and fertile

GPX: Glutathione peroxidase

Theoretically, this process could also support the growth of existing tumors, supplying them with blood to fuel their growth

The inflammation-related damage factors released by cells after ferroptosis activate immune cells that further promote the progression of inflammation by impairing AA-mediated lipid metabolism, decreasing mitochondrial function, increasing oxidative stress, and reducing GPX4

(80) based on the Rush Memory and Aging Project (MAP) demonstrated that higher MK-4 in the brain was linked to better cognitive function and 17%20% lower odds of dementia or mild cognitive impairment, fewer signs of Alzheimer's disease, Parkinson's disease and other forms of neurodegeneration