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Description
Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression

Nrf2 under physiologic conditions exists as a cytoplasmic protein bound to Kelch-like ECH-associated protein 1 (Keap1), keeping Nrf2 ubiquitinated for lysosomal degradation (Itoh et al., 1999

Regulatory nodes upstream of Cys involve intermediate metabolites (e.g

Phytochemicals have emerged as adjuvant and complementary medicines in the treatment of various disorders (Azhar et al., 2023

31-33 However, it remains unknown whether specific patient populations could benefit more from NAC therapy than others