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Furthermore, irbesartan has demonstrated efficacy in mitigating high-altitude hypoxia, pulmonary edema, and left ventricular systolic dysfunction caused by oxidative stress in rat models

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Furthermore, tryptophan can be metabolized by gut microbiota to form indole and their derivates including indole-3-aldehyde, indole-3-acetic-acid and indole-3-propionic acid [176]