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They concluded that the combination of low folic acid intake (800 g) and indoor pesticide exposure led to an increased risk for ASD (aOR 2.5, 95% CI: 1.3, 4.7)

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[143] Similarly, accumbal G9a hyperexpression results in markedly increased histone 3 lysine residue 9 dimethylation (H3K9me2) and blocks the induction of FosB-mediated neural and behavioral plasticity by chronic drug use, [sources 12] which occurs via H3K9me2-mediated repression of transcription factors for FosB and H3K9me2-mediated repression of various FosB transcriptional targets (e.g., CDK5)