Biological half-life
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Description
Differentiation efficiency was quantified by quantitative RT-PCR (qPCR), flow cytometry and immunofluorescence
Dysfunctional astrocytes (e.g., downregulated glutamate-aspartate transporter (GLAST) expression) lead to excitotoxic glutamate accumulation, further promoting calcium influx and necroptosis cascades [37]
Contamination at any step propagates through all subsequent concentrations
Based on this fact, we hypothesized that DPEP1 could be involved in OxPt neurotoxicity, and this could be prevented by the use of DPEP1 inhibitors, as cilastatin [26]
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