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The use of proton pump inhibitors (PPIs) has been associated with an increased risk of vitamin B12 deficiency, particular in older adults and those on long-term PPI therapy. Nutrition Reviews Duration-Dependent Risk Assessment The risk of B12 deficiency from PPIs grows with time

PMID: 25044089

Magnesium is a good example of a mineral that may be included in some IV formulas

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It might not be safe for people with: Allergies to vitamin B12 Lebers disease, which affects eyesight Kidney issues Low potassium levels Not having enough other important nutrients like folic acid and iron