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Additionally, TMAO upregulates clusterin expression, leading to increased levels of -secretase and subsequent deposition of A-amyloid between neurons [87]
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Transcriptomic and biochemical analyses have revealed that SIRT2 regulates vascular senescence, at least in part, by inhibiting the senescence-regulating protein p66Shc and its downstream mtROS
2519 (sem 425) v
