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It is studied in laboratory research for its role in fat oxidation, lipolysis, adipose tissue metabolism, lipogenesis inhibition, and cartilage repair pathway biology without the IGF-1 stimulation, insulin resistance, or receptor-mediated proliferative effects associated with full-length hGH

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Methionine synthase plays a role in the production of purines and pyrimidines, which are building blocks in DNA synthesis

Bergeron R, Ren JM, Cadman KS et al (2001) Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis