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Table Of Contents FDA oversight of dietary supplements The FDA coordinates its oversight of dietary supplements with the Human Foods Programs Office of Food Chemical Safety, Dietary Supplements, and Innovation

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Vitamin B12 is a cofactor in synthesizing methionine, which is essential for protein formation.[ref] If you are deficient in B12 or folate for a long time, you can develop megaloblastic anemia

these were patients that have early disease, given the inclusion criteria was patients who exhibited their first non-Raynaud symptom no earlier than 60 months prior to recruitment in the trial