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Because GSH is implicated in several biochemical processes and regulates other antioxidants, it is often referred to as the master antioxidant. Review The biochemical role of glutathione as a driver of chronic illness Low total GSH levels and elevated ratios of oxidized to reduced GSH are common in chronic illnesses as well as advanced age
Nature 636 , 447456 (2024)
The absence of macrophage Nrf2 promotes early atherogenesis
The discovery of superoxide dismutase in mammals and then in plants underlined the physiological importance of oxygen free radicals in biological cells (McCord and Fridovich 1969
