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[DOI] [PMC free article] [PubMed] [Google Scholar] [46].Kryukov EV, Ivanov AV, Karpov VO, Vasilevich Alexandrin V, Dygai AM, Kruglova MP, et al

As the transformed cells multiply, they outgrow the diffusion limits of oxygen, thus, becoming hypoxic

Although the proposed adverse effects discussed above deserve scrutiny, a pre-clinical safety evaluation by Xu et al

doi: 10.3389/fimmu.2022.1040336

O -GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver
