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Similarly, earlier studies led by Sikiric and colleagues in the 1990s suggested safety and benefit in gastrointestinal conditions such as ulcerative colitis, but these reports were published only in abstracts or local conference proceedings, with no independent replication or peer-reviewed validation

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Functional assays: Quantitative measures such as tensile strength in connective tissue, perfusion imaging, or quantification of cellular infiltration within wounds

IV therapy bypasses digestion for direct elevation