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In human GGT, autocatalytic activation involves an N-O acyl shift at threonine (Thr)-381, which produces an ester bond between the side chain OH group of the Thr and an -carbonyl group of the residue 380, which is the last residue of the N-terminal portion that consequently becomes the large subunit

Physiological reviews

Additional assays commonly measure fatty acid oxidation rates, intracellular lipid accumulation, and downstream signaling intermediates such as cyclic AMP and protein kinase A activation

[23] James Felton, Flint residents frustrated with water problems, WNEM.com, September 8, 2014

Due to oxidative stress, the extracellular matrix glycosaminoglycan structure is destroyed [35]