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The recent evidence shows that the dUTPase protein encoded by EBV and HSV-1 can be transported to the brain via exosomes, where it induces pro-inflammatory cytokine release (e.g., IL-1, IL-6, TNF-) from endothelial cells, astrocytes, and pericytes, thereby degrading tight junction proteins, disrupting BBB integrity and inducing neuroinflammation [80]

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Glutathione and NAC are repurposed supplements that have antioxidant benefits for the respiratory system and exert a positive effect on blood coagulation

doi: 10.1093/oxfordjournals.molbev.a026334 10 ChenC.ChenH.ZhangY.ThomasH