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These genotoxic toxins include the polyketide synthase (pks) pathogenicity responsible for colibactin expression, cytolethal distention toxin (CDT), cytotoxic necrotizing factor (CNF), cycle-inhibiting factor (CIF), and afimbriale adhesin (afa) [144,146,147]
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Moreover, of note is the effect of single-gene knock-out mutants on microbial physiology [93, 94]

The cause of death was neonatal CPT II deficiency
