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Polycythemia vera has also been reported with parenteral methylcobalamin

Side Effects of Excessive B12 Intake Whilst vitamin B12 toxicity is uncommon, several adverse effects have been reported in association with very high B12 levels, though establishing direct causation remains challenging

Adequate maternal intake is important for both the mother and infant during nursing, and maternal requirements for vitamin B12 increase during lactation

In these patients, administration of an NSAID may cause a dose-dependant reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal failure

Sublingual methylcobalamin tablets at 2500-5000 micrograms daily work for patients with mild absorption issues