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Initial research focused on its role in wound healing and tissue remodeling, where it was found to modulate the expression of extracellular matrix (ECM) proteins such as collagen and elastin

G-quadruplexes are secondary DNA structures that have gained significant attention due to their involvement in various biological processes, including aging and oxidative stress

NTP 1993)

For example, both D1- and D2-like receptors have been shown to activate all three members of the MAPK family: p38 MAPK, JNK, and ERK1/2

In a recent report Bateman et al (2013) reported the ability of aspirin to acetylate 120 proteins in HCT15 human adenocarcinoma cells using an alkyneaspirin chemical reporter