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doi: 10.4103/ijo.IJO_646_17

And somewhere in the middle of all that noise, you are left holding a vial of reconstituted peptide with no clear answer on the best way to actually inject it
The lack of clarity regarding the efficacy of certain therapies in helping individuals with IC, owing to the low or very low degrees of supportive evidence, was expressed in a recent Cochrane review [9]

Hofmann S, Hilbe M, Fajardo RJ, Hagenmuller H, Nuss K, Arras M, et al

This is a well-established physiological response