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Description
Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenes

The compound forms S-S mixed disulphide(s) with critical Cys residues or week interactions with the substrate binding site, which are observed as irreversible or competitive inhibition, respectively

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The apparent volume of distribution is 0.45 +/- 0.03 L/kg

c-Myc has been shown to mediate these and others, which are detailed in the section below and highlighted in Fig
