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PMCID: PMC9168854

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A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes

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indeed, SLC25A19 pathogenic variants severely reduce mitochondrial TPP, causing Amish lethal microcephaly and thiamine metabolism dysfunction syndrome 4 (Figure 1) [8]

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Mefferd, C

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Modified alternate-day fasting is similar to ADF, but allows modest calorie intake (1525% of caloric demand) on fasting days

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