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6 The potential of ferroptosis in PD early diagnosis It is estimated that by the time motor deficits are detected and individuals with PD receive a clinical diagnosis, they may have lost 3050% of their dopaminergic neurons, accompanied by a 5060% reduction in striatal dopamine (212), underscoring the critical need for early diagnosis in PD treatment

Recombinant Klotho can enhance cholesterol efflux by inhibiting the Wnt/-catenin signaling pathway, thereby reducing lipid accumulation in foam cells

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Cognitive decline: Research in patients with mild cognitive impairment and early dementia shows Semax slows progression and improves function in some cases