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The products exist in a space where they are legal to sell as supplements but lack regulatory blessing for therapeutic use

One bisamidate to advance to clinical trials is CS-917, a bis-alanine ethyl ester-protected phosphonate, which is an inhibitor of fructose 1,6-bisphosphatase [83]

In those studies, no significant toxic effects have been reported

We investigated their impact on HRQoL and characterized symptom patterns and risk factors to identify at-risk patients

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