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CSCs have been heavily implicated in mediating chemoresistance in many cancers, including glioblastomas, pancreatic and colorectal cancers [22]
In addition to glucose-6-phosphate, H6PD can metabolize other hexose-6-phosphates, as well as glucose-6-sulfate, and glucose
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10.1016/j.devcel.2016.04.018 Dev
Rather than viewing depletion as a single-variable issue, the session emphasized glutathione status as reflective of overall intracellular stress exposure
