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The occurrence of the sub-clinical deficit has been highlighted by their measurement, but its effects have not yet been fully understood [23]

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Namely, the mean age of patients varied between 55.0 and 73.0 years, the mean body weight ranged between 66.0 and 94.0 kg, HbA 1 c levels between 7.6 and 8.5%, the duration of diabetes was 9.016.8 years, and background therapy was insulin with or without metformin (Table S7)