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Instead, it is injected straight into the bloodstream to achieve maximum effectiveness
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doi: 10.26444/aaem/112331

Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses
Thus, specific targeting of IGF-1R signaling post development may prove to be the best approach to achieve the benefits of low growth signals on healthspan and aging, without the potential unwanted side effects of combined adult-onset GH/IGF-1 deficiency