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Description
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It binds with high affinity to hepatocyte growth factor (HGF) and interacts with its receptor, c-Met
Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs
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United Healthcare, Aetna, and Anthem routinely deny J1071 claims submitted without prior approval regardless of diagnosis code accuracy
