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Description
Participants starting above 8% HbA1c often fell by more than 3 points

Chang KH, Basyal M, Alaniz Z, Honma D, Tsutsumi S, Dos Santos CE, Daver, N, Andreeff M

Zhao et al., 2025) that MSCs can not only directly differentiate into nucleus pulposus-like cells, replenishing the missing cell population (Li et al., 2025), but also play a key role through paracrine actions: on one hand, by secreting growth factors (such as TGF-, IGF-1) to activate anabolic pathways and promote ECM synthesis (Tang et al., 2025)

It is synthesized from the amino acid histidine
An in vivo test for genotoxicity, generally a test for chromosomal damage using rodent hematopoietic cells, either for micronuclei or for chromosomal aberrations in metaphase cells
