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The compound's sleep-promoting and related general physiological effects after intraventricular (brain), intravenous, and intraperitoneal application in different mammalian species have since been confirmed

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Furthermore, by delivering antioxidant proteins, MSC-EVs can inhibit NP cell apoptosis, thereby delaying the progression of intervertebral disc degeneration (IDD) in organ culture models (Liao et al., 2019)

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I-FAPB is a protein present in differentiated enterocytes, and damage to the epithelial layer results in this protein being released from cells hence, it is considered an indicator of epithelial damage [74]