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This selectivity is particularly important for individuals seeking pure fat reduction rather than body recomposition, those who do not want muscle hypertrophy for aesthetic or functional reasons, athletes in weight-class sports who need fat loss without muscle gain, individuals with contraindications to growth-promoting interventions, and those concerned about cell proliferation effects

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Patients With Chronic Disease: Diseases such as inflammation and impaired immune function can be regulated by peptides

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Jastreboff and colleagues (NEJM, 2023) reported substantial body-weight reduction in obesity research populations, and Rosenstock and colleagues (Lancet, 2023) documented glycemic and weight effects in type-2 diabetes research populations