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Intrathecal Pathogenic Anti-Aquaporin-4 Antibodies in Early Neuromyelitis Optica
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The rate of Grx1-mediated protein deglutathionylation varies substantially between 1.75 10 5 and 4.0 10 2 M 1 s 1 which is heavily dictated by the pKa of the target thiol (e.g., the lower the pKa the faster the rate) and accessibility (Jensen et al., 2014)
