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This paper found that the most severe observed G6PD mutations interfere with dimerization and allosteric binding sites
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Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, et al
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Although water-referenced quantification avoids reliance on metabolite ratios (e.g., Cr-normalization), it is not without limitations
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