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What the authors report is that a 5 day treatment which almost abolished morphine analgesia in wild type mice produced no tolerance in knock-in animals [77]

Once hydrated and glucose 250 mg/dL (may be lower in euglycemic DKA) Arterial pH: 12) due to unmeasured ketoacids Sodium: Low (due to osmotic dilution) Potassium: May be normal or high initially, but total body K is deplete BUN/Creatinine: Elevated due to dehydration F

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9 Where IF is present, a deficiency can easily be overcome by oral supplementation of crystalline cobalamin, which does not need to be cleaved from food proteins