glutathione content calculation Randomized Clinical Trial of How Long-Term Supplementation Offers Protection from Oxidative Damage and Improves HbA1c in Elderly Type 2 Diabetic Patients Ratio of reduced glutathione to

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Experimental Gerontology , 45 , 78

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Main limitation: selectivity figures (such as an in-vitro ~11.7-fold preference for senescent cells) come from cell models, not humans

5 Conclusion and future perspectives Despite the significant advancements in understanding the role of ferroptosis in MIRI, there remain notable limitations that need to be addressed